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to organic fertilizers so as not to mess up
the plant's hormonal balance during flowering and seed production.
There have been recent reports of a wholly new source of lysergic
acid amides. The so called Sleepy Grass (Stipa robusta) of the desert
areas of the American West is reported to have an alkaloid content
approaching that of ergot, and should be a good source of raw
material to feed into acid production. See Discover magazine, Dec.
Additional Reading On Growing Ergot:
Gulf Res. Rep. 3(1), pages 105-109 (1970), "Observations on
Claviceps purpurea on Spartina alterflora." Canadian Journal of
Botany Vol. 35, pages 315-320 (1957), "Studies
on Ergot in Gramineous Hosts." Pharmacognosy (1965), pages 321-
327. Agricultural Gazette of New South Wales Vol. 52, pages 571-
(1941), "Artificial Production of Ergot." Pythopathology Volume
35, pages 353-360 (1945), "The Field
Inoculation of Rye With Claviceps purpurea." American Journal of
Botany Volume 18, pages 50-78 (1931), "The
Reactions of Claviceps purpurea to Variations in Environment."
Extraction And Isolation Of
The Lysergic Acid Amides
Extraction And Isolation Of
Lysergic Acid Amides
After the harvest of the crops, the farming phase of acid
production is now over. This is a good news/bad news situation for
the acid chemist. The good news is that the voluminous pile of crop
will in short order be reduced in size to a quantity more conveniently
handled in the lab. For example, ergot typically contains from V* to
¥2% alkaloids by weight. A 200 pound harvest of ergot will, after
extraction, yield Vi to a full pound of lysergic acid amides. This
quantity is worth several millions of dollars if moved wholesale at a
dollar per dose. The yield from a similar amount of morning glory
seeds will be reduced by a factor of about 5, but still be substantial.
Hawaiian baby woodrose seeds are intermediate between the two.
The bad news takes several forms. A significant amount of
solvents will be needed to perform the extraction from the crop. It is at
this juncture that the acid chemist will need to employ industrial
contacts, theft, or the formation of a front operation to get the several
55-gallon drums of solvents needed to execute the extraction. The
aroma that solvents give off also precludes doing this procedure in a
residential neighborhood. A shed back on the farm site or a business
front setting is much more suitable.
It is also at this phase that the delicate natures of the lysergic
molecules express themselves. While they are locked up in ergot or in
seeds, these molecules are pretty stable, so long as the crop is kept
Practical LSD Manufacture
cool, dry, and free from mold. Once they are released, they are prey to
light, heat, air, and bad chemical handling. A clock begins to tick on
the shelf life of your product. Once the extraction is begun, the
chemist must consider himself committed to the task, and not allow
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